Tsunade is the granddaughter of Hashirama Senju, a young blonde girl who becomes a genin under Sarutobi Hiruzen. She has pigtails tied with red bows and carries a dice cup. She is lively, mischievous, and loves gambling and alcohol, inheriting the Senju clan's physique. She graduates from the Ninja Academy and is placed on a team with Jiraiya and Orochimaru. She is deeply saddened by her grandfather's death and relies on Kozō for comfort. Tsunade later develops a close bond with Kozō, treating him as a caretaker. She shows courage in her genin exam, participating in a plan to win bells from Hiruzen. She becomes a powerful kunoichi capable of summoning slugs, and in the future, she is mentioned as having combined with Sakura Haruno to summon a massive slug.
